Hi Stannarad, I don't think I could take MSM in a pill form, far too rough on the tum. I use a powder that I sprinkle over my breakfast grains and stir well before adding rice milk, so it's diluted. In the evening I disolve the MSM powder in A fizzy 1gm C vit with a big glass of water, and always eat somthing at the same time.I have 2 old horses and a retired racing greyhound that will take MSM quite readily in their feeds. The powder will disolve easily in water, and seems to be better assimilated by the body.Love and Light, Deotima.