This is the exact scenario I'd like to avoid by adding in with the humaworm some Clarkia-like Herbal Extract (black walnut, wormwood, cloves). By adding in I mean wash the humaworm pills down with a couple drops or so of the extract in water. I do not see how 2 pills would be as effective for a larger person that is 250 - 300 pounds, as they are for 100 - 200 pound ppl.