I haven't gotten into heavy duty cleansing of other organs yet, but I do take Homozone as a colon cleanser. I use it on an on-going basis, 1-teaspoon every evening. I went with the Homozone because it is activated with lemon water which soothes the gallbladder. When I don't take it right after a cleanse, I go through toxicity and feel AWFUL. I also take 1oz of Goji everyday, I can't say why, but it gives added relief. I don't want to be without Homozone or Goji until I'm DONE!!