Information please

My wife had a hysterectomy in her mid 20's. She is 41 now.
Her doctor at the time prescribed hormone replacement. I don't remember the brand name, but it was estrogen and testosterone, for her lower sex drive. Although she stopped using it after two or three years, her voice has deepened considerably since.
She is very self-consious about this.
Anyway, if anyone knows of a way to reverse this, please respond.

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