As I have suffered with constipation since I was young I can provide some insight on this. Enemas (Fleet) will make your grandmother dependant and they are very dangerous. The only thing that has ever helped me is Dr Schulze Intestinal Formula 1. I take one herbal pill daily with dinner and I go to the bathroom at least once a day. I have been taking it for 3 years now and it has saved my life litterally.
I was prescribed some pills from my doctor and it almost killed me... These herbal pills do not work like exlax. They get your intestines and colon moving by strenghening the muscles that move the food. The site is www.800herbdoc.com I am not trying to sell anything nor do I have any ties to this site. I just think it is a good product. I hope your grandmother gets better.