2:22 is a progression from 2 to 4, but still using all the talents of the 2, and amping up the 2 to a master number vibration, 22, which is the number of Buddha/Builder.
2 stands for relationships, balance, two points that create a line. 2 is all about life, as life comes in pairs - yin/yang, light/dark, male/female.
22 stands for the person who wants to achieve something concrete. The Master Builder who, like Frank Lloyd Wright, inspires people through form.