I know I had(have) several Gallstones that showed up on ultrasound. I can tell you that since I started flushing in October of last year, I have lost 35 pounds, my allergies have cleared up, and my shoulder pain is almost gone! I dont really have attacks anymore but just some slight pain every now & then when I eat bad for a few days. Each person is different so just keep flushing & Good Luck!!