New Study: Beneficial Effects Of Ketogenic Diet In Obese Diabetics

June 16, 2005 Newsletter


New Study: Beneficial Effects Of Ketogenic Diet In Obese Diabetic Subjects

At the 87th Annual Meeting of the Endocrine Society, in San Diego, June 4-7, Professor Hussein M. Dashti and his colleagues from Kuwait University presented the results of their latest ketogenic diet study.

In this latest study, the effect of a ketogenic diet in obese subjects with high blood glucose level was compared with that in subjects with normal blood glucose levels for a period of 56 weeks.

Sixty-four otherwise healthy obese subjects with body mass index greater than 30, having high blood glucose level (Group I) and those subjects with normal blood glucose level (Group II) were selected.

All 64 subjects were instructed to follow a ketogenic diet consisting of less than 20g of carbohydrates and 80 to 100 g of proteins. Polyunsaturated and monounsaturated fats (5 tablespoons olive oil) were included in the diet. Twelve weeks later an additional 20 g of carbohydrates was given. Micronutrients (vitamins and minerals) in the form of 1 capsule/day were given to each subject.

The body weight, body mass index, the level of blood glucose, total cholesterol, LDL cholesterol, tryglyceides and urea all showed a significant decrease from week 1 to week 56 whereas the level of HDL cholesterol increased significantly. Interestingly these changes were more significant in Group II subjects as compared to Group I. Changes in the level of creatinine were not statistically significant.

The researchers concluded: "This study shows the beneficial effects of ketogenic diet in obese diabetic subjects following its long term administration. Furthermore, it demonstrates that in addition to its therapeutic value, low carbohydrate diet is safe to use for a longer period of time in obese diabetic subjects."

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