In Dr Schulze's book he states that you are to start off with one capsule. If you do not notice any difference in your bowel behavior by the next day,to increase the dosage to 2 capsules. You continue to increase your dosage every evening by one capsule until you notice a dramatic difference in the way your bowel works. He states that there is no limit and that even some people have needed to take over 30 capsules to get a bowel movement. I had been taking 9 capsules a night for over a week because that is how many I need to get my bowels working. It was not the pills that made me sick it was my gallbladder. Everyone is different, there is no one size fits all. Everyone's body works in different ways, what makes you sick might not make me sick. Maybe you should get Dr Schulze's book "Healing Colon Disease Naturally". It might help you.