It is my understanding (from the boards and Andreas' books) that Colosan will eventually clean the mucoid plaque from the small intestine and the colon. It is a gentler process than some of the other programs that are available. Andreas discusses it in his Liver Clease book and in the Rejuvenation book. I would also recommend checking out the wealth of information in some of the many posts on the other 3 Ask Andreas boards.
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I am just starting a cleanse using mag oxides - so my information is not first hand yet.