I did the first round of ParaGone full strength, waited the five days(during which I did a gallbladder cleanse) and now am on the 2nd day of the 2nd round of ParaGone, full strength. I find the timing a tad difficult(they recommend taking the capsules 3 hrs after food and I am a grazer)but I can live with it for two more weeks. When I started the 2nd round I felt quite awful for half a day but I don't know whether it was because of the flush, the ParaGone or something else. I feel better now, tho the bowels are still loose. I did notice the stools were noticeably darker during the ParaGone regime.