Pantethine, and Beta Glucan from oat bran!

If cholesterol levels are dangerously high, whack them back with Pantethine, which forms Master Enzyme A, the only thing that neutralizes the toxic byproduct of Candida, Acetaldehyde. Should make you suspicious of Candida...Or go the cheap route: OAT BRAN! Lower cholesterol, whack back Candida, and get the miracle of heightened immunity just from cheap ol' OAT BRAN! Or buy the expensive yeast-derived supplements...Read on:

Recent experiments completed at Baylor College of Medicine in the laboratory of Professor Phil Wyde also prove the oral effectiveness of beta-1,3-glucan to stimulate nonspecific immunity11. Peritoneal macrophages doubled their phagocytic activity in mice fed with beta-1,3-glucan. This systemic effect of oral application of beta-1,3-glucan is comparable to that achieved using injections, which makes this material a unique and very valuable oral immunostimulant.

When beta-1,3-glucan was added to Antibiotic regime in animals challenged with different bacterial (Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli and others) and viral (Herpes virus) pathogens, a reduced amount of Antibiotics or antivirals was needed to cope with the infection11. It also has an antifungal effect, shown in experiments with Candida albicans11. Such a broad anti-infective spectrum of beta-1,3-glucan can be explained only by the fact that the immunostimulation produced by this unique material is non-specific.

Continuing research with oral application of beta-1,3-glucan revealed that it increases the effectiveness of other oral cholesterol-reducing agents, such as Niacin and Lopid19. Interestingly, recent research has also demonstrated the anti-diabetic effect of IL-1 cytokine, which increases insulin production resulting in lowering of blood glucose level20. Macrophages are the main source of IL-1 in the body and it's production can be boosted by beta-1,3-glucan supplementation. Mindful of the extremely high rate of atherosclerotic complications and the extraordinary requirement for antioxidants in diabetic patients, beta-1,3-glucan is an obvious adjuvant for an improved lifestyle in these conditions.

As is repeatedly shown in the multitude of studies concerning the activity of beta glucan as an immune stimulator, or perhaps more descriptive, a "biological defense modifier", there are enormous benefits to be obtained by the use of beta-1,3-glucan as a nutritional supplement. The aging process has been defined as "the sum total of life's physical embarrassment due to adverse conditions"; in this regard, beta-1,3-glucan may well be the first and only true anti-aging supplement. It is defensive to negative events such as infection, tumors and radiation damage and adjunctive to the positive effects of antioxidants, lipid balance enhancers, Antibiotics and other therapeutics. The result is improved general health which means more enjoyment of life, less infirmities, less time and money required for medical needs and potentially dramatic savings in Medicare and other health related expenditures over time.

Beta-1,3-glucan is effective in all mammals as it is in fish and birds. It successfully prevents vibriosis, yersiniosis and furunculosis in Crustacea when it is added to the feed7,21,22. The new devastation of the shrimp farm, the Taura Syndrome, which has been recently identified as viral disease, causes high mortality with survival of less than 20% of the shrimp farm population. Feeding shrimp with beta-1,3-glucan increases their survival rate up to 90%23.

Beta-1,3-glucan basically is a highly purified form of a food product. Technically it is a polysaccharide molecule completely made with glucose. Glucose is a simple saccharide that the body transforms to energy as ATP and stores in muscles, liver and other tissues in a form of glycogen. Beta-1,3- glucan is different from energy-storing glucose-containing polysaccharides because the connection between the glucose units is different, more specifically, it is the beta-1,3-linkage, which makes this compound so unique. It is Generally Recognized As Safe (category GRAS according to FDA) and has no toxicity or side effects24.

To summarize, beta-1,3-glucan is a safe and very potent nutritional supplement with a systemic effect that can be described as non-specific immune stimulation combined with it's free-radical scavenging activity. Some of the biological events illustrating this stimulation are:

Activation of macrophages, expressing increased nonspecific phagocytic ability allowing macrophages to destroy pathogens more efficiently, frequently preventing disease.

Release of important cytokines, such as IL-1, IL-2 among others, initiating immune cascade and triggering other cell lines, such as T-cells. Release of colony-stimulating factors, boosting bone marrow production.

Cholesterol-reduction through cell activation and anti-oxidant activity.

Groups of people that are considered to benefit from beta-1,3-glucan supplementation:

People with impaired immunity from any cause including but not restricted to HIV infection; people with high occurrence of infectious diseases, tumors and undergoing chemotherapy and radiotherapy; age 40+ when the natural aging process starts to slow down immune reactivity, geriatric patients, and others with a compromised immune response.

People that are possibly can be affected by extra free-radical production caused by external sources: ones frequently exposed to low-dose radiation, including sun light, other types of exposures such electromagnetic fields; lack of raw fruits and vegetables in diet and eating preserved food. Extra free-radicals can also be a result of a chronic disease such diabetes or chronic inflammation.

People who exercise excessively, professional and amateur athletes as well as people who workout intensively and also those under physical or emotional stress who have a temporary immune deficiency which can result in infection. Beta-1,3-glucan will provide them with nonspecific immunostimulation that can increase their resistance to illness.

People with high risk of atherosclerosis should definitely add beta-1,3-glucan to their diet whether they are taking cholesterol-reducing drugs or not. Macrophage activation will not only help to draw extra cholesterol from the blood but it also can prevent further plaque formation on the arterial walls and phagocytize existing plaque which is recognized as a foreign body.