The importance of oral zinc (preferably picolinate) in adolescent Acne is supported by zinc deficiency in schizofrenic (criminal) patients and by usefullness of oral zinc picolinate in the treatment of schizophrenia (for ex Pfeiffer) and inflammatory Acne (for example Michaelsson, 1977; Meynadier, 2009; Yamaoka, 2000).
To prevent zinc intoxication (copper deficiency) oral zinc (11-22 mg/d) can be combined with vitamin B3 (niacinamide 75 mg/d for ex 1/d VM-75 Solgar), chromium, selenium, vitamin B5, vitamin E, NAC (Nacetylcysteine or cysteine or cistine), biotin (B8 5 mg/d), lipoate and a few of copper.
(www.forumfree.net/?c=3428 in italian)