i also noticed the new primal defense formula. the same goes for their enzyme product, omega-zyme. i contacted the company and they say that every so often they tweak their product, to 'make it better'. yeah right. i was doing well on the old primal defense formula but the new one makes me tired all the time. i don't know if it's because it has gluten or not, or maybe because it is in fact more effective. i don't know why they would go from a hypo-allergenic supplement to a hyper-allergenic one. it makes no sense whatsoever. the lady that i spoke to at garden of life said that it's just 'more honest labelling'. she says that they couldn't guarantee that the old formula was gluten free either! i don't think she knows what she's talking about. i don't think it's right to change the formula without indicating so clearly on the bottle. i bought the new formula thinking it was the same and spent the next three days in bed.