DMSO must be used carefully or it will drive in any contaminants into the system. For example don't expose to latex or it may induce latex reactions. DMSO must be very pure but studies have shown DMSO will soften stony tissue. Research this carefully and don't be fooled by horror stories as it is FDA approved for Interstitial Cystitis. There's a nice DMSO link at Silver Colloid forum. God bless.