what do you mean it doenst work? what doesnt work the cleanse?the portal vein is blocked somewhat either due to the crohns some how from birht? trauma from surgery...no one knows...have had 2 resections for the crohns and the gall bladder removed Since the gall bladder removal I have not been right. I first got sepsis during a"routine" liver check(with the big needle in your side) and then whenever they near the liver or poke around there I turn yellow and fever to the point of "you better get vancomiacin NOW or Im DEAD!" Id rather go herbal and homeoptahic then thsi drastic...Im totally freaked!