Caprylic Acid is good to whack back Candida that can bore through the G.I. tract and induce Leaky Gut. The best form of ALA is R-Alpha Lipoic Acid, available on the net, and is good to heal up Leaky Gut. I would take R-ALA with the main meal, and Caprylic Acid before bedtime (and upon arising if desired). Both are quite useful and not harmful together to my knowledge.