Hi. Yes I heard that the Japaneese scientists worked on that one. I've never used it, but if I had it, I would start to crowd out the yeast [they won't like it] by taking triple the dose and adding acidophilus and any other probiotic. Plus find a good prebiotic to go with them [certain foods] Keep it up and don't let up ....if you can afford it! My probiotic/enzme regime is costing about $10.00 a day shroom