ThreeLac is primarly a probiotic. I don't recall ever reading cautions about taking fiber along with probiotics, and doubt if this would be an issue. Just the opposite, actually. Sufficient fiber intake is critical for promoting beneficial bacteria in the gut. Gut pH is largely determined by the digestion of fiber by gut bacteria, and pH (low/normal/high) has a dramatic effect on the types of bacteria and pathogens present. So, consuming fiber should compliment and boost any probiotics one might take.