That's a very personal decision. You must weight the specific reasons you are taking it against how it will affect the cleanse. Please put much thought into this because, while many posters may suggest you just quit because it puts a burden on your liver and such, if it will put you in a terrible dark place to quit then you shouldn't.
I've struggled with Depression since I was a child and know when I'm on a medication that is working well, it is hard to remember why I'm taking it after awhile. Please take the time to listen to what your body needs. If your Depression is severe than be cautious before making any changes.