Hi. No way to really measure but since it is topical, usually not a problem. I just filled a small glass dropper bottle with DMSO and then dropped in a dose or 2 or wormer. Gave it some time to dissolve. I had good results with ivermectin and fenbendazole. Be careful with moxidectin (Quest) as it is the same class as Ivermectin but much stronger and lasts MUCH longer so can accumulate. Too much IVM can be an issue & cause eye damage. Good luck.