Hello, I not sure of you read the book the amazing liver and gallbladder flush but it states in the following the flush protocol that toxins(stones) trapped in the colon for longer than 2-3 days after the Liver Flush they can start to create irritation, infection, headaches, abdominal pain, bloating, loss of appetite, thyroid problems, ITCHY SKIN, skin eruptions and more. They recommend doing a few colonics or enemas after each cleanse to insure that all stones are completely out of the colon after a flush.