The Icing on the Cake

        THE CAKE OF FORGOTTEN CATARACT CURES

A delicate base of light therapy sponge, filled with layer upon layer of crystallin de-aggregators,

and topped with a delicious icing of AGE crosslink breaker.

 Happy Birthday: 100 candles to celebrate 100 years of wilful negligence, and candles are still being added!

 If and when the cake is cut and we get to eat it, we will remove the candles.

Yes, it's true that people want a quick solution to medical problems. But I think the main reason why people are satisfied with the present situation as regards cataract surgery is because they were falsely told there are no alternatives, and they believe surgery is the only way to save their sight.
Quite the reverse. Since I got cataracts about 5 years ago, I discovered that nonsurgical treatments and cures had already been successfully practised since 100 years ago, sometimes for decades. However these cures were all ignored and consequently obscured by the ophthalmology profession. The result is that when cataract patients visit their eye doctor and are told that today, there's nothing except surgery, the doctor is perfectly right. What the patient does not know is that this lack of nonsurgical alternatives has been deliberately contrived.
Of course, this tragedy is not unique to the ophthalmology profession - it runs through all of modern medicine, but that only makes it worse.
My purpose is to tell people about this, so that they demand what is rightfully theirs - a nonsurgical treatment of cataract. Either the one that existed in the past, or one based on new discoveries which were - I believe deliberately - never implemented.
Broadly speaking, cataract is due to the malfunction of the chaperone protein known as 'alpha-crystallin' in the human lens, which normally keeps the lens optically clear. This protein can lose its chaperone function in one or both of two ways:
1) it 'misfolds' into larger aggregates or clumps,
2) it gets 'shackled' by other chemical molecules which latch onto it and prevent it from functioning properly.
Any nonsurgical cataract treatment must try to reverse either one or both of these two problems, but the goal is the same - to restore the 'chaperone' function of alpha-crystallin.
One such method that existed in the past was the colored light ray therapy practised by Dr. William Luftig from around 1914 to 1958, and by Robert Brooks-Simpkins in the 1960's and 70's. The colors and irradiation times used were highly individualized for each patient precisely because each patient has a different mix of the above two factors. Thanks to their long experience, these doctors knew which color wavelengths would work in which people. Now, these forgotten pioneers have passed away. But since we know from the many books they wrote that this method does work, the eye profession has a huge responsibility to start from scratch again, built up an empirical database of color wavelengths and cataract types, and try to reproduce the earlier results without wasting any more precious time. Anything less is betrayal by the eye profession of the trust invested in them by humanity to care for our eyes.
In a similar vein to color ray therapy of cataract, the ability of violet light to photobleach the human lens was discovered in 2010 (after color ray therapy had been ignored for 100 years). But violet light may work only when the alpha-crystallin is shackled to derivatives of the aminoacid tryptophan, not when it is shackled to AGEs. It therefore remains to be seen whether this one wavelength alone (violet) can be used to treat everybody's cataracts.
The second method, never properly trialed by ophthalmologists, is that of eyedrops. Since 1956, various kinds of eyedrops have been developed, each of which may work on different types of cataract. A good example is the formulation developed at MIT in 1986 which prevents crystallins clumping together. Although it may not work when alpha-crystallin is bound to other molecules, this remarkable discovery could still have treated cataracts in millions of people if it had been implemented. But last year, one of the lead researchers who created those formulations proudly boasted to me that he himself had had cataract surgery. When I asked him why he had not taken his nonsurgical discovery further, he blamed his boss at MIT.
More recently, in 2015, it was found that lanosterol and some other sterols could reverse cataract. However even if sterols do correct the misfolding of alpha-crystallin, it is difficult to see how they could break its strong attachment to other molecules, particularly AGEs like imidazolone which gives the lens a yellow discoloration and makes everything look yellow.
                           The Icing on the Cake
Yet a discovery was made at the University of Arkansas in 2008 which showed that even the strong attachment between alpha-crystallin and AGEs can be broken by chemical agents known as 'AGE crosslink breakers'. It was further shown that the alpha-crystallin thus liberated from its AGE shackles then recovers all of its 'chaperone' function.

https://link.springer.com/article/10.1007/s11010-008-9797-2

The implications of this are staggering: an eyedrop containing such an 'AGE crosslink breaker' would wipe senile cataract off the face of the earth. Despite which, predictably, neither the University of Arkansas nor the ophthalmology profession have taken this any further. I am sure that cataract patients knew nothing of this. It is my fervent hope that, by bringing this to the attention of patients and others who still care about humanity, they will compel the eye profession to admit that it has not acted in their best interests. Cataract patients and the readers of CureZone have no means to produce sterile eyedrops. But the eye profession does have the means, not to mention the responsibility. If the profession continues to shamelessly profess ignorance of this discovery, then I would like to see them legally obliged to rectify the situation by producing these eye drops for clinical use so that human beings no longer have to needlessly risk their sight in the surgery.