Re: PPZ and PZQ antagonism, Nausea and Stone herbs binding AChE

Matt, I was talking about the pyrantel and piperazine antagonizing each other. Andreas Kalcker and you have also mentioned this before. So, if i take pyrantel with ppz, together, at 6 am, will they not just stop each other from working?

Pyrantel pamoate has a short duration of action and tends to a complete elimination from the body in the feces and urine within 3 to 4 days. Pyrantel pamoate is poorly absorbed from the gastrointestinal tract, and approximately 6 to 8% total is found in the urine and the remainder in the feces.
The recommended adult dose is one daily dose. Children of 12 years and older, 40 to 75 kg: 3 tablets. Adults over 75 kg: 4 tablets. Its incompatible with the use of piperazine, a substance naturally found in pumpkin seeds or the antiparasitic containing this substance in their formulation since they cancel or neutralize each other .

http://oldweb.andreaskalcker.com/en/health/parasite/116-parasite.html