I took about 1/4 of a 500g tablet this morning and felt like I was on fire - it might be the brand because I used to take B3 and I flushed but not like this. I just took another 1/4 and the flush wasn't bad at all. I could feel it, but it didn't hurt.
So I'll try what you said with lesser amounts - that makes sense.
I'm going to take the B3 with my systemic enzymes, COQ10 and when I resume the Paragone in a few days, I'll take it with that too.
I haven't felt anything crawling in days since I started the megadosing of COQ10 and systemic enzymes.