The SIS machine and SIS electrodes completely and accurately fulfill the specifications of the patented and patented methods of inducing tissue repair and regeneration developed by American orthopedic surgeon, Robert O Becker:
Becker’s discovery of a means of promoting in situ ‘reverse’ de-specialization of fibroblast cells to provide a new population of hematopoietic-like stem cells is employed. These newly modified cells are available to remodel existing tissue and form completely new tissue during the Proliferative and Remodeling Phases of wound healing, to an extent not normally possible in the animal body (with some notable exceptions, e.g. the salamander).