Re: Resistance to meds may be a myth
I don't have strongyloides, but
Ascaris has filiare larval stages.
I tried Invermectin for weeks into months, fenben, albendazole, the whole lot, none of it worked, no reaction even at levels that made me blind, (vision returned) levels as high as i read in studies, levels that were calculated to keep me alive and kill the invader. None worked.
Then I found magnesium, potassium, magnesium sulfate, spirulina, and zinc sulfate. I built a base on balancing the body with minerals and metals, and fixing my immune system, and going from chore to chore. I explored kidney flush, liver flush, lipid chemistry, citric loops, ROS loop, Urea Loop. After I made the body function, I had a fighting chance.
Then I retested anti-parasitics, and low and behold they worked. Not earth shattering, but they worked.
I think that the missing element between the test tube and practice is nutraceuticals.
Along the way I found parallel low level Alinia, Invermectin, Piperazine Citrate, and Diethylcarbamazine were able to completely eliminate migrans in my body in about 3 weeks.
Granted the migrans larval stage of
Ascaris is not strongyloides, but in my mind, they are close.
Few people realize
Ascaris actually has about 7 stages. It is like having 7 infections in one, and fighting all kinds of the infection in parallel is required to win.
I suspect that strongyloides is similiar, and that a similiar approach would work.
I finally took care of ascaris, at 42mg/kg/D, and lost my hair in the process. A funny thing happened as the last Ascaris worm died, I saw tomato skins again.
I now turn to fascioliasis, which seam not to be killed by my initial praziquantel dosing a year ago. Having them burn in delicate CNS areas is not fun, but with the knowledge and the power a year of research provides, I now know 10mg/kg/D Albendazole and 88ml powder/kg/D Praziquantel is sufficient to kill the flukes.
I suspect if the drugs do not work ~ as one expects, ~ it is because:
1) The body is to ill to fight, the body has to be within limits to have antiparasitics work
2) One parasitic infection can enable another, making the identity, or fighting the other infection much more difficult.
That is why I think the drugs do not work. I always suspected #2 above was my problem, and when tomato skins came out at 42mg/kg/D of albendazole, it identified my secondary invader that had been alluding me for a year.
Good Hunting.