I don't think Miracle-Mineral-Supplement would be helpful for adrenal fatigue or hypothyroidism. The hypothyroid forums are loaded with information about both. Doctors, BTW, are mostly ignorant on these subjects and aren't even ordering the right blood tests. If you are still on Synthroid or one of its generics, you are definitely not being treated effectively. The book, "Stop The Thyroid Madness" has much to say that will point you in the right direction (including solutions for adrenal fatigue). Also the book "Hypothyroidism, Type 2".