I once took a steroid called trenbolone acetate (TA). It is supposed to dampen your cortisol receptors. In other words its supposed to keep you anabolic. Well, after taking it I got a really bad Acne infection on my chest. I tried everything and it wouldn't go away. I thought I was going to die from the pain and itch, not to mention how horrid it looked. I went to all types of doctors and nothing!!!! Until I read about what TA does to the cortisol receptors, and what cortisol does to the body, and how it helps fight inflammatory infections, etc. I finally convinced one doctor to just give me a prescription for cortisol. Wow! my chest cleared in 4 days!!! I was so happy! Be careful with drugs out there that lower cortisol, if you get an infection, your screwed!!!! just my two cents...