From what I gathered from the previous answers is yes it is safe to do the coffee enemas when you no longer have a gall bladder. Apparently the gall bladder is just a storage port for bile, but the liver can do this itself without the gall bladder. I also had the same question myself as I no longer have my gall bladder. I'm happy that someone from the Gerson Foundation answered this question, as I have just recently came across this information.