I have major back pain in my upper back and hip/lower back. It think it is because there are toxins that hide in all the crevices of our joints, and our backs are a prime location for that. The pain I think comes from the release of the toxins and replenishment of new, healthy cells. This is just my understanding, but I know that last time my back pain intensified, then as I cleansed it went away, then afterward it STAYED away and as long as i kept sugar-free, I never had joint pain.