Dysbiosis of Gut Fungal Microbiota is Associated With Mucosal Inflammation in Crohn’s

http://journals.lww.com/jcge/pages/articleviewer.aspx?year=9000&issue=00000&a...


"this is the first study to determine the differences of fungal composition and diversity between inflamed and noninflamed mucosal area in CD patients."

"The opportunistic fungal pathogens, such as C. albicans and C. tropicalis, are abundantly observed in the inflamed mucosa, whereas they are absent in the noninflamed area (Fig. 1E). Candida species scarcely colonize in the gastro- intestinal mucosa in healthy subjects.36 The data observed here suggest that Candida species, especially C. albicans, might be a potential candidate for the diagnosis of mucosal inflammation in CD. In addition, G. moniliformis, A. brassicicola, and C. neoformans are prevalently present in the inflamed mucosa (Fig. 1F)."