My son can't tolerate probiotics, they turn pathongenic, he is on diflucan and I would say that grapefruit seed extract was one of the strongest antifungals you could take to kill candida. What about Pine Cone Extract some people on here say that is very good to and garlic is a good one. My son can't hardly tolerate many natural anti fungals because if he could he would not be on diflucan because I think that those medications should be left when you really need them such as a life threatening situation. My son has become immune to nystatin after only one year.