Microbes in submucosa different from lumen

They determined that there was a "normal" submucosal bacterial community (microbiome) in both health and disease that was different from the bacteria present in the mucosal and luminal populations, Dr. Chiodini explained in an interview. They also determined that total bacterial counts within the diseased Crohn’s tissues were several hundredfold higher than the counts found in normal tissue, added Dr. Chiodini, formerly of the department of internal medicine, Texas Tech University Health Sciences Center, El Paso.

http://www.obgynnews.com/news/top-news/single-article/study-identifies-distin...


So stool tests may be waste of money since they don't correlate with what's inside the intestinal walls underneath the mucosa.