High dosing vitamin C picked me up from the first severe crash of my life in May of 2012....but then put me in an even bigger crash 5 months later once my body started to "reject" any dose of vitamin C. I am still unable to take Vitamin C....even one gram. It's really weird and I am still having trouble understanding why after 9 months going off I am still having trouble tolerating Vitamin C. It makes me super wired and then Bam I'm like a dead person for 2 days afterwards. And btw I chelated from metals using cutler's protocol, IV DMPS, cilantro/chlorella for about 11 months...and that was 6 months prior to my major crash.