Re: Bromide poisoning: psychiatric symptoms and negative anion gap

"Until the middle of the 20th century, when bromide was removed from such over-the-counter products as Dr. Miles’ Nervine and Bromo-Seltzer, chronic bromism was reported to be responsible for approximately 5-10% of admissions to psychiatric hospitals."

Yes, this is hardly recognized these days!!

"hallucinosis is the rarest of the bromide psychoses. It differs from delirium in that the patient is oriented. The object of this paper is to consider some aspects of this condition, especially its relationship to schizophrenia.

In an earlier article1 figures were given from mental hospitals showing a total of 74 bromide psychoses in 2,273 first admissions. The breakdown showed 10 cases of simple intoxication, 48 of delirium, 13 of transistory schizophrenia, and 3 of hallucinosis. (These figures do not reflect the true incidence of simple bromide intoxication, for patients with this disorder seldom reach a mental hospital.)

Bromide delirium is well known and needs no comment. “Bromide schizophrenia” is the term applied to cases in which the intoxication precipitates a transitory hallucinatory-paranoid schizophrenia,2 with features which are listed below. It has long been known that in patients with a schizoid personality toxemia"
http://archpsyc.jamanetwork.com/article.aspx?articleid=487772


- I repeat; "hallucinosis is the rarest of the bromide psychoses" !!!