My next treatment is Evening Primrose Oil, which might finally do the trick although I might have to take it for life to prevent deficiency. I applied vitamin c powder to my lips in the past, not fruit. The constant moisturizing treatment is more of a natural treatment so do not be so fast to bash natural treatments. The most natural treatment I have tried is drinking milk to remove the protective film on resistant bacteria in my mouth. It seems like it has decreased dental plaque, but I have not yet combined it with anti-bacteria treatment to know how well it works. My lips are not healed, but they have improved since I have started drinking milk again.