I know that James (HV) talks about methylation quite often and I am still confused. Local Dr had me do a DNA test for MTHFR (cause of many health problems)and put me on folate to compensate. Said folic acid not good. Did more research and found some YouTube videos on “MTHFR”. Still hard for me to understand it all despite the diagrams, but maybe you can make some sense to it. This DR says he sees a lot of infertility patients having this MTHFR factor.