Choose carefully and realize that food is the best medicine of all. The colon is the source of most problems and mineral deficiency causee disease, so best course of action is to heal the colon and take in lots of usable minerals in their natural state. Keep in mind those selling supplements can be as bad as the drug companies and it all involves money. All cultures that have long lives have one thing in common. They all take in tremendous amounts of minerals best place to get minerals is from a plant based source.