Ive recently started an Miracle-Mineral-Supplement protocol and have read the books Jim Humble wrote to guide me. He says you need to add 5 drops of activator (I use plain lemon juice) to one drop pf Miracle-Mineral-Supplement solution and let it stand for three minutes. You can smell the chemical change happening (don't inhale too much of it). Then use it as soon as possible after the three minutes. It slowly loses it's punch if you leave it for an extended period of time. He says if you can't get to it within 10 minutes, still use it, it just won't be as potent. Im still learning but I thought this might be of help.