Re: Feel worse on zinc and b6

Riboflavin (B2) helps B6 absorbtion - with pyroluria riboflavin deficiency is likely to be present too.

What type of B6 are you taking? Any other form apart from P5P require magnesium and B2 to be absorbed otherwise absorbtion is reduced by up to 60%:

http://naturalinsight.hubpages.com/hub/Pyroluria-A-Hidden-Disorder


"There are 3 natural forms of Vitamin B6 found in food - Pyridoxine, Pyridoxamine and Pyridoxal. Pyridoxal joined with a phosphate is the metabolically active coenzyme form used within our bodies, also known as P5P. Pyridoxine hydrochloride is the more commonly used form of supplement for vitamin B6, and is well utilised in most individuals. However the body is then required to convert the pyridoxine into P5P in the small intestine so it can be utilised. The pyridoxine can not be used by the body directly. Two metabolic steps must first be performed - phosphorylation and oxidation. These processes require nutrients like Zinc, Magnesium and Riboflavin (Vitamin B2). If Riboflavin is low, P5P production can be reduced by up to 60%. For this reason in the treatment of Pyroluria it is important to administer the P5P form, as deficiencies in Zinc, Magnesium and B2 are most likely to be present." Tweet