In 1944, the use of penicillin was initiated during World War II. At that time, there were 0 studies on candida albicans. As antibiotic use increased, so did the associated research into candida albicans. The number of studies has increased from 0 studies in 1944 to a total of 1,401 in 2011. A search on PubMed now yields close to 28,000 studies since 1945. That’s enough research for - http://candidaplan.com/blog/524/candida-antibiotics-and-the-intestinal-flora/