cannot lose

Hi

I have been 2.5 stonne over weight for 3 years now. I have lost 14 lbs since start of the year.

No matter what I do now, I cannot lose weight now.

I am in me 40s, I do have sedentary job. I am trying to up my exercise.

had blood tests for low thyroid etc. Did have elevated liver enzymes, ALT.

hospital said weight loss was way forward.

I dont drink or smoke, and was extremely fit in my 20s, 30s .

My mum ballooned with weight when she turned 40 something, I do believe that could be factor, genetic inheritance

my food intake is lowish carb, no bread, wheat. I believe I am consuming around 1500 cals per day

I have tried :

CLA
B12
Kelp
Vitamin D, calcium

all to aid weight loss. Jury still out on some of any potential benefits. Mum did have thyroid problems, and was diabetic toward end of her life.

just at wits end, I do not know which way to turn,

all positive advice welcome,