Ultimately, the whole enterprise of medical Science and pharmacology is about safety and efficacy.
No, ultimately the whole enterprise of medical science and pharmacology is about making money - and safety has often been a far secondary consideration.
Hopefully, instead of just more trials and development of yet more patentable and highly profitable ways to unnaturally interfere with out bodies mainstream science will look more towards nature to help us naturally prevent and heal disease.
Cardiovascular disease, including artery health, is a great example. The right diet, lifestyle, nutrition items and herbal supplements as needed can prevent and heal inflamed and clogged arteries, atrial fibrillation and much, much more.