Re: Regulation of Candida albicans morphogenesis by fatty acid metabolites.
Please translate in practical terms.Thanks.
In short they are saying that Candida can exist in two forms. As a yeast or as a fungus. In its yeast form it is harmless, so they are testing what will cause or prevent its conversion in to its dangerous fungal form. In the fungal form it forms finger-like projections known as hyphae, and pseudohyphae, that allow the Candida to dig in to tissues causing tissue damage.
Then they go on to say that the presence of inflammatory prostaglandins, a type of hormone, increase the conversion of the Candida in to its dangerous form. But some fatty acids can prevent this by blocking the prostaglandins. Omega 3 fatty acids reduce inflammatory prostaglandins.
Then they mention that the fatty acids produced by our flora also prevent the conversion of Candida in to its dangerous fungal form.
I posted this because it further confirms that the acidity of the flora is what keep Candida from growing out of control and in a benign yeast form.