Thanks Joe- I really need the encouragement to push on. The most debilitating symptom was that I had insomnia and could not sleep on 12.5mg. This is what made the round a disaster. ON the 25mg my head pressure was so bad I could barely stand it. SO now what you are saying is that with added magnesium and vit c I am more likely to tolerate the dmsa? Should I take more herbal laxatives so I am excreting better? Also, should I be taking a yeast killer such as nystatin at the same time as taking the chelator? I'm sorry for all these questions. Do you think dmps will do me any good since I have high levels of lead? Thanks loads - I need added support at this time.