At first, my nutritionist thought that I was just noticing wrinkling that had been occuring throughout the past year as a result of AF. However, after he ran a biomeridian test (i.e., using a device to measure energy pathways in the body) on me, it showed issues with my skin. He gave me some glucosamine. He is extremely knowledgebale about all aspects of nutrition, but not so much with the wrinkling.