Re: Candida and Gluten Intolerance

Another possible connection between environmental illnesses and celiac disease involves the gut flora. Various studies have shown disturbances of the healthy gut flora in environmental illnesses and many doctors who specialize in treating them advocate treating overgrowth of Candida and bacteria in the intestines. Research published in the prestigious medical journal The Lancet in 2003 proposed that Candida in the intestine may act as a trigger for the production of antibodies against gluten and the intestinal tissue which cause celiac disease. This assertion is based on the fact that the yeast Candida contains proteins that are identical and very similar to those found in gluten, including gliadin. Candida also triggers the same tissue transglutaminase and endomysial enzymes involved in celiac disease. It is therefore possible that changes in levels and behavior of Candida in the intestines may result in an immune response to the organism which is then transferred to gluten and intestinal tissues due to the common proteins they contain. The end result would therefore be celiac disease (10).

“Is Candida albicans a trigger in the onset of coeliac disease?” was the title of a research article published in the highly respected medical journal, The Lancet [reference below]. The researchers found Candida albicans contains a protein in its cell wall called “hyphal wall protein 1” or HWP1 that is very similar in its structure to components of gliadin. In addition, Candida can actually use its human host’s tissue transglutaminase to adhere to the intestinal wall. Researchers are looking at the possibility that when Candida becomes attached to a person’s intestines and their immune system tries to get rid of it, antibodies are produced that attack both gliadin and transglutaminase, since these are similar or identical to components within Candida’s cell wall. Unfortunately, these antibodies could also trigger full-blown celiac disease in the unsuspecting person. This is yet another reason why overgrowth of Candida is not to be taken lightly. The researchers went further to hypothesize that some patients who are gluten intolerant but do not improve with a gluten-free diet, might be able to improve if Candida overgrowth was effectively treated.

  "It is also very beneficial and strongly recommended to avoid gluten in grains and casein (milk protein) in dairy products, as common underlying allergies to these proteins may cause damage to the intestinal villi (finger-like hairs that absorb nutrients in the intestines). When food molecules are not absorbed, they produce decay in the small intestines that provides more fuel for candida to proliferate."