Sorry, I don't have any experience with immune modulators. I too have hypothyroid symptoms so if you take it and find that it works please let me know. I'm in the first process of taking my temps daily to see if I even have hypothyroid because the docs say I don't but found out that the blood tests aren't accurate and I can still have a slight problem. So what hypothyroid symptoms do you have? Once my hypothyroid issue is confirmed I will advice you. Will do some research on Cat's Claw information. Thanks!!!