I had debilitating anxiety/panic attacks/heart palpitations and also Depression when I had Mirena in (had it for 3 1/2 months), but once I took it out, they got much more manageable. I have had it out for 6+ weeks now, and thank GOD I have gotten better each day. I feel kind of bad posting a positive message on here because of all of the poor women who are still having terrible issues even after removal, but I hope mine is a message of hope for some. Now having said that, I know I could be in for crashes in the future, but right now, I'm good. So... my advice is to get it out asap and expect that you will probably have some lingering symptoms, but the sooner you get it out, the sooner you can get back to being you. Hope that helps if only a little. Good luck!!